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Gdańsk University of Technology

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Synthesis of malonylenamides and thiomalonylenamides

5-[Hydroksyl(aryl(amino))methylene]-2,2-dimethyl-1,3-dioxane-4,6-dione is convenient source of ketenes which can be trapped with various nucleophiles like alcohols, thiols and amines. In reaction between in situ generated ketene and enolizable imines we can easily obtain corresponding malonylenamides. This facile method can be used to obtain thiomalonylenamides using 5-[sulfhydrylo(alkyl(amino))methylene]-2,2-dimethyl-1,3-dioxane-4,6-dione as a source of ketenes.

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Additional information

Category
Aktywność konferencyjna
Type
publikacja w wydawnictwie zbiorowym recenzowanym (także w materiałach konferencyjnych)
Language
angielski
Publication year
2011

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