Crystal structures, UV-Vis and EPR spectra and magnetic properties of four copper(II) complexes with chloride anions and 4-methylimidazole, 2-ethylimidazole, 2-isopropylimidazole or 2-ethyl-4-methylimidazole are described. In the solid state three of the complexes are mononuclear and one complex with 2-ethylimidazole is binuclear with bridging chlorido ions. UV-Vis spectra of the methanolic solutions of the complexes show LMCT bands characteristic for the presence of Cu-N(imidazole) and Cu-Cl coordination bonds. The visible part of the UV-Vis spectrum indicates that in solution the complexes adopt similar geometries. Powdered compounds exhibit anisotropic X-band EPR spectra: axial for complexes with 4-methylimidazole and 2-ethyl-4-methylimidazole and rhombic for the complex with 2-isopropylimidazole. Spin-spin interaction between Cu(II) ions in the binuclear complex with 2-ethylimidazole has mainly dipole-dipole character. In frozen methanol solutions the EPR spectra of all studied complexes prove similar axial symmetry of the coordination polyhedra. The results of cytotoxicity tests of the complexes against U937 lymphoma show comparable, moderate antineoplastic activity of the tested compounds.
Authors
Additional information
- Category
- Publikacja w czasopiśmie
- Type
- artykuł w czasopiśmie wyróżnionym w JCR
- Language
- angielski
- Publication year
- 2013
