Publications Repository - Gdańsk University of Technology

The correlation among selenium uptake, the content of bioactive compounds in sprouts, and biological activities triggered in cultured human cells by sprout extracts was investigated. Seeds of Brassica crops and rye were treated with SeO2 water solution. The selenium levels in sprouts increased from 1.0-4.1 to 53.3-382 μg/g dw with no influence on plant physiology according to the indices used. Neither the composition of glucosinolates (GL) in Brassica sprouts nor the myrosinase activity nor the composition of GL breakdown lipophilic products were significantly affected. In all Brassica sprouts, conversion to health-promoting isothiocyanates (ITC) and indoles corresponded to only 1% of total GLs. Low ITC concentration may explain observed lack of induction of glutathione S-transferases (GST) and quinone oxidoreductase (NQO) detoxifying enzymes in HT29 cells exposed to sprout extracts. The insignificant impact on cell growth and genome function suggests that Brassica sprouts may be safe vehicle of selenium to combat its dietary deficiency.

Authors

• mgr inż. Anna Piekarska link open in new tab ,
• Dominik Kołodziejski link open in new tab ,
• Tadeusz Pilipczuk link open in new tab ,
• Małgorzata Bodnar link open in new tab ,
• prof. dr hab. inż. Piotr Konieczka link open in new tab ,
• dr hab. inż. Barbara Kusznierewicz link open in new tab ,
• F.s. Hanschen,
• M. Schreiner,
• Joanna Cyprys link open in new tab ,
• Milena Groszewska link open in new tab ,
• prof. dr hab. inż. Jacek Namieśnik link open in new tab ,
• prof. dr hab. inż. Agnieszka Bartoszek-Pączkowska link open in new tab