Cyanides are widely applied in industrial activity, including gold and silver mining and the production of organic chemicals. HCN is also formed directly from fossil fuel combustion sources from gasoline and diesel vehicles. In natural environment, in plants seeds for example an apple seed, it exists as a cyanogenic glycosides. The amount of cyanide ions originating from food products is however rather small. Larger concentrations of this ion result from the tobacco smoke inhalation. Cyanide is toxic to organisms because it disputes the electron transport chain in the mitochondria membrane and prevents respiration. The aim of this research was to develop analytical procedure and its use to study the urine samples. Determined cyanide ion concentrations in 40 samples of urine that were collected from healthy volunteers exposed to tobacco smoke (active smokers) and environmental tobacco smoke (passive smokers). Cyanide detection was achieved by IC – PAD. Some parameters such as linearity (y=0,0248x+0,1069 R=0,997), precision (SD:0,003 CV:1%) and limit of detection (LOD: 0,1µg/l) of the purposed method were investigated.
Authors
Additional information
- Category
- Aktywność konferencyjna
- Type
- materiały konferencyjne indeksowane w Web of Science
- Language
- angielski
- Publication year
- 2016
