In patients with haematological malignancies, the bowel remains the main source of Escherichia coli bloodstream infections. We present the clinical example of recurrent bowel-blood translocations of E. coli with the unique virulence characteristics in a 55-year-old male with the diagnosis of acute myeloid leukaemia. The virulent factors profile of examined strains confirmed that the co-existence of genes papC, sfa, usp and cnf1, encoding virulence factors, predisposes E. coli to translocation from the gastrointestinal tract to the vascular bed. The close cooperation between haematologists and microbiologists is essential to improve the outcome of patients colonised with highly pathogenic strains.
Authors
- dr hab. Beata Krawczyk link open in new tab ,
- Anna Śledzińska,
- Agnieszka Piekarska,
- Dr n. med. Andrzej Hellmann,
- prof. dr hab. Józef Kur link open in new tab
Additional information
- DOI
- Digital Object Identifier link open in new tab 10.1007/s13353-017-0393-6
- Category
- Publikacja w czasopiśmie
- Type
- artykuł w czasopiśmie wyróżnionym w JCR
- Language
- angielski
- Publication year
- 2017
