We studied the presence of triazole resistance of 121 Aspergillus fumigatus clinical isolates collected in two Polish cities, Warsaw and Wrocław, to determine if resistance is emerging in our country. We identified five itraconazole resistant isolates (4.13%) carrying the TR34/L98H alteration in Cyp51A gene, four of which were cross-resistant to posaconazole and one to voriconazole. One isolate was intermediate susceptible to itraconazole and harbored no Cyp51A alterations. The study confirms the presence of azole resistant A. fumigatus strains in Poland at a level that is comparative to other European countries.
Authors
- Urszula Nawrot link open in new tab ,
- Ewelina Kurzyk link open in new tab ,
- Maiken Cavling Arendrup,
- dr inż. Martyna Mroczyńska link open in new tab ,
- Katarzyna Włodarczyk link open in new tab ,
- Beata Sulik-tyszka,
- Marta Wróblewska,
- Marek Ussowicz,
- Przemysław Zdziarski,
- Katarzyna Niewińska,
- dr hab. inż. Anna Brillowska-Dąbrowska link open in new tab
Additional information
- DOI
- Digital Object Identifier link open in new tab 10.1093/mmy/myx012
- Category
- Publikacja w czasopiśmie
- Type
- artykuł w czasopiśmie wyróżnionym w JCR
- Language
- angielski
- Publication year
- 2018
