Publications Repository - Gdańsk University of Technology

Immunomodulation is one of the significant therapeutic strategies. It includes both stimulation or suppression of the immune system by a variety of substances called immunomodulators, designed to regulate the immune response of the organism to infections of varying etiology. An example of such a substance is tuftsin (TKPA) 3 (Fig. (1)). Tuftsin is an endogenous immunomodulator of a wide spectrum of biological activity. Tetrapeptide 3 provides also antitumor, antimicrobial, anticoagulant and analgesic properties. In this paper, we presented tuftsin derivatives described over the years, its biological activity and potential clinical applications.

Authors

• Agnieszka Siebert link open in new tab ,
• dr inż. Monika Gensicka-Kowalewska link open in new tab ,
• dr hab. inż. Grzegorz Cholewiński link open in new tab ,
• prof. dr hab. inż. Krystyna Dzierzbicka link open in new tab