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Gdańsk University of Technology

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Antimicrobal and ostheointegration activity of bone cement contains nanometals

Purpose: One of the major problems in bone surgery are infections – especially thoseoccurring in the course of the operating on the patients with lowered immunity system,because they carry the danger of complications. In the Mechanical Department of TechnicalUniversity of Gdansk, there has been carried the research with the use of bone cement andmetal nanoparticles.Design/methodology/approach: The bone cement was used without supplement orwith one or two drugs. These experiments are the latest, because include pure bone cement(without drugs) with nanometals. The titanium specimens was covering with such composecoating. The implant was inserted into rat`s thigh for six weeks. Afterwards the implantwas removed from the body and examined by means of scanning electron microscope.Simultanously biological research was carried out. Bonless samples were placed intobacterial liquid, generated by the researcher (the Patent number P 409082 ) containing fivemost frequently occurring bacteria in human body.Findings: Result of the SEM research was positive – there was good adhesion ofostheoblasts to the surface and there were no traces of infection.Practical implications: The research concerns bone cement with nanoparticles proves,that nanoparticles are the alternatives to antibiotics.

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DOI
Digital Object Identifier link open in new tab 10.5604/17348412.1225753
Category
Publikacja w czasopiśmie
Type
publikacja w in. zagranicznym czasopiśmie naukowym (tylko język obcy)
Language
angielski
Publication year
2016

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