In this paper, an investigation into detecting immunosuppressive medicine in aqueous solutions using a spectrometry-based technique is described. Using optical transmissive spectrometry, absorbance measurements in the spectra range from 250 nm to 1000 nm were carried out for different cyclosporine A (CsA) concentrations in aqueous solutions. The experiment was conducted for samples both with and without interferent substances—glucose and sodium chloride. Using a dedicated algorithm, the measured data was analyzed and a high correlation coefficient R2 = 0.8647 was achieved. The experiment showed that the described technique allowed for the detection of various CsA concentration levels in a selective, label-free and simple way. This method could be used in medicine, veterinary medicine and laboratory diagnostics.
Authors
- Marcin Marzejon link open in new tab ,
- Monika Kosowska link open in new tab ,
- dr inż. Daria Majchrowicz link open in new tab ,
- Barbara Bułło-Piontecka,
- dr. Michał Wąsowicz,
- prof. dr hab. inż. Małgorzata Szczerska link open in new tab
Additional information
- DOI
- Digital Object Identifier link open in new tab 10.3390/s18072001
- Category
- Publikacja w czasopiśmie
- Type
- artykuł w czasopiśmie wyróżnionym w JCR
- Language
- angielski
- Publication year
- 2018
