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Gdańsk University of Technology

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Dynamics of a simplified HPT model in relation to 24h TSH profiles

We propose a simplified mathematical model of the hypothalamus-pituitary-thyroid (HPT) axis in an endocrine system. The considered model is a modification of the model proposed by Mukhopadhyay and Bhattacharyya in [10]. Our system of delay differential equations reconstructs the HPT axis in relation to 24h profiles of human in physiological conditions. Homeostatic control of the thyroid-pituitary axis is considered by using feedback and delay in our model. The influence of delayed feedback on the stability behaviour of the system is discussed.

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DOI
Digital Object Identifier link open in new tab 10.14708/ma.v46i1.6389
Category
Publikacja w czasopiśmie
Type
artykuły w czasopismach recenzowanych i innych wydawnictwach ciągłych
Language
angielski
Publication year
2018

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