Bone lesions resulting from large traumas or cancer resections can be successfully treated by directly using synthetic materials or in combination with tissue engineering methods (hybrid). Synthetic or hybrid materials combined with bone tissue’s natural ability for regeneration and biological adaptation to the directions of loading, allow for full recovery of its biological functions. Increasing interest in new production methods or various types of regenerative membranes and shaped scaffolds means that methods such as additive manufacturing can significantly accelerate the preparation of constructs used in the further biological adaptation of natural tissue. The porosity that allows not only ingrowth of the natural tissue, but also the ability of the synthetic material to transfer loadings in the skeletal system during the regeneration interval, will have a significant impact on regenerative capacities. This work presents the results of preliminary analyzes of bone models in the field of mechanical strength for monotonically and cyclically loading conditions. The determined material constants, such as ultimate tensile strength, Young modulus, and toughness or fatigue life, can be used in numerical simulations of new membranes for the regeneration of damaged bone tissue.
Authors
Additional information
- DOI
- Digital Object Identifier link open in new tab 10.1016/j.biosystems.2019.01.001
- Category
- Publikacja w czasopiśmie
- Type
- artykuły w czasopismach
- Language
- angielski
- Publication year
- 2019
