D-xylose reductase is a member of the aldo-keto reductase family, and is involved in D-xylose and L-arabinose conversion through the Pentose Catabolic Pathway (PCP) in fungi. In this study, we biochemically characterized a newly identified second D-xylose reductase (XyrB) from Aspergillus niger. This NADPH-dependent reductase is able to efficiently convert D-xylose and L-arabinose, and it has the highest affinity for these sugars of all currently known fungal pentose reductases. A combination of biochemical data, transcriptomics and phylogenetic analysis further illustrated the role of XyrB in the PCP.
Authors
- mgr inż. Agata Terebieniec link open in new tab ,
- Tania Chroumpi,
- Adiphol Dilokpimol,
- Maria Victoria Aguilar-Pontes,
- Miia R. Mäkelä,
- Ronald de Vries
Additional information
- DOI
- Digital Object Identifier link open in new tab 10.1016/j.btre.2021.e00610
- Category
- Publikacja w czasopiśmie
- Type
- artykuły w czasopismach
- Language
- angielski
- Publication year
- 2021
