There is a growing awareness that the large number of environmental pollutants we are exposed to on a daily basis are causing major health problems. Compared to traditional studies that focus on individual pollutants, there are relatively few studies on how pollutants mixtures interact. Several studies have reported a relationship between environmental pollutants and the development of cancer, even when pollutant levels are below toxicity reference values. The possibility of synergistic interactions between different pollutants could explain how even low concentrations can cause major health problems. These intricate that molecular interactions can occur through a wide variety of mechanisms, and our understanding of the physiological effects of mixtures is still limited. The purpose of this paper is to discuss recent reports that address possible synergistic interactions between different types of environmental pollutants that could promote cancer development. Our literature studies suggest that key biological pathways are frequently implicated in such processes.
Authors
- Francisco Alejandro Lagunas‐Rangel,
- Jenni Viivi Linnea‐Niemi,
- dr hab. inż. Błażej Kudłak link open in new tab ,
- Michael Williams,
- Jörgen Jönsson,
- Helgi B. Schiöth
Additional information
- DOI
- Digital Object Identifier link open in new tab 10.1029/2021gh000552
- Category
- Publikacja w czasopiśmie
- Type
- artykuły w czasopismach
- Language
- angielski
- Publication year
- 2022