Sulfonamides are the first successfully synthesized antimicrobial drugs. The mechanism of sulfonamides’ antimicrobial action involves competitive inhibition of folic acid synthesis and prevention of the growth and reproduction of bacteria. Even though they have been applied in therapy for more than 75 years, sulfonamides are still the drugs of choice for the treatment of various diseases. The aim of this work was to synthesize and characterize two new sulfonamides hydroxyphenyl moiety and investigate their ability to form complexes with Rh(III). The results of recent studies indicate an increased interest in the application of potential platinum-group metal ion complexes as an alternative, promising candidates for anticancer and antimicrobial drugs.
Authors
- Małgorzata Gawrońska,
- Mateusz Kowalik,
- Joanna Duch,
- dr hab. Katarzyna Kazimierczuk link open in new tab ,
- dr Mariusz Makowski
Additional information
- DOI
- Digital Object Identifier link open in new tab 10.1016/j.poly.2022.115865
- Category
- Publikacja w czasopiśmie
- Type
- artykuły w czasopismach
- Language
- angielski
- Publication year
- 2022
