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Gdańsk University of Technology

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Wavelet transform analysis reveals differences between patients with impaired LVEF and healthy individuals

Heart failure (HF) is a global pandemic. It af- fects 64 million people worldwide, with stead- ily increasing incidence, morbidity, mortality, and economic burden [1]. Forecasts indicate continued rising prevalence, especially among the elderly and in low-to-middle socio-de- mographic index regions [2]. Left ventricular ejection fraction (LVEF) significantly impacts HF treatment and prognosis [3]. The sequence of physiological changes related to reduced LVEF remains uncertain, and only limited re- search has explored these mechanisms. This study employed wavelet transformation (WT) to investigate oscillatory interactions, exploring aging and decreased LVEF effects on cardiovascular dynamics. We analyzed central (electrocardiogram [ECG]) and pe- ripheral (blood pressure [BP]) measurements, hypothesizing modified wavelet quantities in HF patients compared to healthy individuals.

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