Repozytorium publikacji - Politechnika Gdańska

Background: Recently, we described a model system which included corrections of high-resolution computedtomography (HRCT) bronchial measurements based on the adjusted subpixel method (ASM).Objective: To verify the clinical application of ASM by comparing bronchial measurements obtained bymeans of the traditional eye-driven method, subpixel method alone and ASM in a group comprised ofbronchial asthma patients and healthy individuals.Methods: The study included 30 bronchial asthma patients and the control group comprised of 20 volunteerswith no symptoms of asthma. The lowest internal and external diameters of the bronchialcross-sections (ID and ED) and their derivative parameters were determined in HRCT scans using: (1)traditional eye-driven method, (2) subpixel technique, and (3) ASM.Results: In the case of the eye-driven method, lower ID values along with lower bronchial lumen area andits percentage ratio to total bronchial area were basic parameters that differed between asthma patientsand healthy controls. In the case of the subpixel method and ASM, both groups were not significantlydifferent in terms of ID. Significant differences were observed in values of ED and total bronchial area withboth parameters being significantly higher in asthma patients. Compared to ASM, the eye-driven method overstated the values of ID and ED by about 30% and 10% respectively, while understating bronchial wall thickness by about 18%.Conclusions: Results obtained in this study suggest that the traditional eye-driven method of HRCTbasedmeasurement of bronchial tree components probably overstates the degree of bronchial patencyin asthma patients.

Autorzy

• Grzegorz Mincewicz,
• prof. dr hab. inż. Jacek Rumiński link otwiera się w nowej karcie ,
• dr Grzegorz Krzykowski link otwiera się w nowej karcie