Repozytorium publikacji - Politechnika Gdańska

Pharmaceutical products can be contaminated by residues of solvents, reagents (used for the synthesis) or degradation products. Impurities in drug may pose a risk to human health and life, therefore analysis and identification of impurities in pharmaceutical products is veryimportant and inevitable.High performance liquid chromatography coupled with mass spectrometry (MS) is very useful technique for identification impurities in pharmaceuticals. Moreover it is ideally suited to the analysis of known or suspected compounds. However, MS does not give detailed structural information (for example, generally it is not possible to distinguish between isomers). More structural information can be obtained using LC-NMR, therefore using of this two techniquessimultaneously can give complementary structural information for unknown polar and nonvolatile compounds.

Autorzy

• mgr inż. Kamila Wilczewska link otwiera się w nowej karcie