Repozytorium publikacji - Politechnika Gdańska

An analysis of the phylogenetic distribution and virulence genes of Escherichia coli isolates which predispose this bacteria to translocate from the urinary tract to the bloodstream is presented. One-dimensional analysis indicated that the occurrence of P fimbriae and α-hemolysin coding genes is more frequent among the E. coli which cause bacteremia. However, a two-dimensional analysis revealed that a combination of genes coding two adherence factors, namely, P + Dr, P + S, S + Dr, S + fim, and hemolysin + one adherence factor, were associated with bacteremia and, therefore, with the risk of translocation to the vascular system. The frequent and previously unrecognized co-existence of pro-inflammatory P fimbriae with the invasion promoting Dr adhesin in the same E. coli isolate may represent high-risk and potentially lethal pathogens.

Autorzy

• Kasjan Szemiako link otwiera się w nowej karcie ,
• dr hab. Beata Krawczyk link otwiera się w nowej karcie ,
• Alfred Samet,
• Anna Śledzińska,
• Bogdan Nowicki,
• Stella Nowicki,
• prof. dr hab. Józef Kur link otwiera się w nowej karcie