Repozytorium publikacji - Politechnika Gdańska

The UvrA protein is a DNA-binding and damage-recognition enzyme which participates in the prokaryotic type nucleotide excision repair (NER) pathway. It has recently been noted that some bacterial genomes comprise additional uvrA genes which encode five distinct types of UvrA homologue. We investigated the sequences of over 2400 bacterial genomes and found 130 examples of bacteria containing uvrA 2 genes. The sequence analyses conducted on these UvrA homologues revealed that the previously established division of UvrA proteins might be based on some incorrect assumptions. In this paper, we present the reasons for our creation of a new division of UvrA homologues and a description of the four UvrA classes we have created.

Autorzy

• Marta Marszałkowska link otwiera się w nowej karcie ,
• dr hab. inż. Marcin Olszewski link otwiera się w nowej karcie ,
• Magdalena Bil link otwiera się w nowej karcie ,
• Łukasz Kreft link otwiera się w nowej karcie