Repozytorium publikacji - Politechnika Gdańska

The protection of methionine and the reduction of methionine sulfoxide in methionine-containing analogues of Gly-His-Lys are described. The peptides were synthesized by a solid-phase method using the standard Fmoc procedure. Simultaneous deprotection of the peptide side chain and liberation from the resin were achieved using an appropriate TFA cocktail. The TFA cocktail was selected to minimize oxidation of the methionine residue. The reversible method of methionine oxidation was also studied. Selective identification and quantitative analysis of the methionine-containing peptides are based on an LC–MS study.

Autorzy

• Monika Kukowska link otwiera się w nowej karcie ,
• Magdalena Kukowska-Kaszuba,
• prof. dr hab. inż. Krystyna Dzierzbicka link otwiera się w nowej karcie