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Functionalization of indium-tin-oxide electrodes by laser-nanostructured gold thin films for biosensing applications

of a relatively large area formed by pulsed laser nanostructuring of thin gold films arereported and discussed. The SEM inspection of modified electrodes reveals the presence of the nearlyspherical and disc-shaped particles of dimensions in the range of 40–120 nm. The NP-array geometry canbe controlled by selection of the laser processing conditions. It is shown that particle size and packingdensity of the array are important factors which determine the electrode performance. In the case ofNP-modified electrodes the peak current corresponding to the glucose direct oxidation process showsrise with increasing glucose concentration markedly higher comparing to the reference Au disc electrode.The detection limit reaches 12 M and linear response of the sensor is observed from 0.1 to 47 mM thatcovers the normal physiological range of the blood sugar detection.© 2015 Elsevier B.V. All rights reserved.1. IntroductionThe importance of nanomaterials for science and technologysteadily increases during last decades. The noble metal nanopar-ticles

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