Repozytorium publikacji - Politechnika Gdańska

Studies described in this work were related to the bulk synthesis and characterization of polyurethanes (PURs) obtained with the use of cyclic 4,4′-methylene bis(cyclohexyl isocyanate) (HMDI) or linear 1,6-hexamethylene diisocyanate (HDI), amorphous α,ω-dihydroxy(ethylene-butylene adipate) macrodiol (PEBA), 1,4-butandiol (BDO) chain extender and dibutyltin dilaurate (DBTDL) catalyst. Obtained PURs were modified with l-ascorbic acid (AA). Raw materials and modifier improving biocompatybility were carefully selected due to the planned use of obtained PURs as a tissue scaffold fabrication material. Performed chemical structure studies (FTIR, ATR-IR, 2D NMR), morphology observations (SEM, TEM and AFM) and characterization of degradation profile revealed that PURs obtained by using HDI were representing a significantly better characteristic than those obtained by using HMDI. Thus, the HDI-based PURs were suggested for further development as a materials useful for tissue scaffolds fabrication in the field of tissue engineering.

Autorzy

• dr inż. Iga Gubańska link otwiera się w nowej karcie ,
• dr hab. inż. Justyna Kucińska-Lipka link otwiera się w nowej karcie ,
• prof. dr hab. inż. Helena Janik link otwiera się w nowej karcie