Repozytorium publikacji - Politechnika Gdańska

The synthesis and crystal structures of (E)-3-(4-hydroxybenzylidene)chroman-4-one, C16H12O3,I, and (E)-3-(3-hydroxybenzylidene)-2-phenylchroman-4-one,C22H16O3,II, are reported. These compounds are of interest with respect to biological activity. Both structures display intermolecular C—H---O and O—H---O hydrogen bonding, forming layers in the crystal lattice. The crystal structure of compound I is consolidated by pi–pi interactions. The lipophilicity (logP) was determined as it is one of the parameters qualifying compounds as potential drugs. The logP value for compound I is associated with a larger contribution of C---H interaction in the Hirshfeld surface.

Autorzy

• Kamil Suchojad,
• prof. dr hab. inż. Anna Dołęga link otwiera się w nowej karcie ,
• Angelika Adamus-Grabicka,
• Elżbieta Budzisz link otwiera się w nowej karcie ,
• Magdalena Małecka