Repozytorium publikacji - Politechnika Gdańska

In this paper, we review the structure-activity relationship of OGF and its analogues. We highlight also OGF derivatives with analgesic, immunomodulatory activity and the ability to penetrate the blood-brain barrier and may be used as safe agents enhancing chemotherapy efficacy and improving quality of life in cancer patients. The reviewed papers indicate that Met-enkephalin and its analogues are interesting candidates for the development of novel, non-toxic, and endowed with an analgesic activity anticancer drugs. More preclinical and clinical studies are needed to explore these opportunities.

Autorzy

• mgr Justyna Budka,
• mgr inż. Szymon Kowalski,
• mgr Monika Chylińska,
• prof. dr hab. inż. Krystyna Dzierzbicka link otwiera się w nowej karcie ,
• Iwona Inkielewicz-Stępniak