Repozytorium publikacji - Politechnika Gdańska

A new simple method for the synthesis of 2-ethynylphenyl(diaryl)phosphine oxides via ring opening of benzophosphol-3-yl triflates has been developed. This process occurs via nucleophilic attack of a Grignard reagent at the phosphorus center, which results in ring opening and cleavage of a leaving group. The reaction proceeds under mild conditions and, within 15−60 min, leads to a library of previously unavailable 2-ethynylphenylphosphine oxides in yields up to 98%.

Autorzy

• dr hab. inż. Łukasz Ponikiewski link otwiera się w nowej karcie ,
• dr Sylwia Sowa