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Recent items
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One-step recovery of REE oxalates in electro-leaching of spent NdFeB magnets
- Irina Makarova
- Jacek Ryl
- Zhi Sun
- Irina Kurilo
- Karolina Górnicka
- Markku Laatikainen
- Eveliina Repo
Recovery of rare-earth elements (REEs) from spent NdFeB magnets is receiving great attention because of high amount of neodymium and potential risk of environmental pollution. In this study, a novel environment-friendly hydrometallurgical route is proposed for efficient recovery of REEs during electrochemical leaching with sulfuric and oxalic acids. With proper adjustment of the electrolyte composition and operating conditions, effective separation of different elements is observed; a compact layer of REE oxalates in a purity of up to 93% is obtained on the cathode, while iron remains in the solution and as solid residue for further recovery. The mechanisms during the electro-leaching process were subsequently investigated and we propose that cathodic deposition of the REEs is due to electrostatic attraction of the REE-oxalate particles on the cathode. With this finding, selective recovery of REEs from spent magnets can be achieved. This study provides a new insight on electronic waste recycling by implementing principles of electrochemistry.
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On-line measurement of wood surface smoothness
- Jakub Sandak
- Kazimierz Orłowski
- Anna Sandak
- Daniel Chuchała
- Piotr Taube
The latest progress in the field of optics and microelectronics resulted in development of new generation vision systems capable of scanning surface topography with very high sampling frequencies. The blue color of illuminating light as well as novel systems for controlling ultra-thin laser line thickness allows measurement of the porous surface of wood with a triangulation method. Three alternative sensors were tested here in order to verify their suitability for determination of surface topography in the industrial environment. The scanning head was installed at the exit zone of the four-side profiling moulder and was set to scrutinize the wood surface shape line-by-line, immediately after profiling. The sensor was also tested for automatic detection of surface defects appearing on elements after sanding, wetting and painting with diverse finishing products. The set of pilot test results, together with an original algorithm for real-time surface defects detection, is presented.
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Open Data Capability Architecture - An Interpretive Structural Modeling Approach
- Adegboyega Ojo
Despite of increasing availability of open data as a vital organizational resource, large numbers of startups and organizations fail when it comes to utilizing open data effectively. This shortcoming is attributable to the poor understanding of what types of capabilities are required to successfully conduct data related activities. At the same time, research on open data capabilities and how they relate to one another remains sparse. Guided by extant literature, interviews of these organizations, and drawn from Interpretive Structural Modeling (ISM) approach which are pair comparison methods to evolve hierarchical relationships among a set of elements to convert unclear and unstructured mental models of systems into well-articulated models that act as base for conceptualization and theory building, this study explores open data capabilities and the relationships and the structure of the dependencies among these areas. Findings from this study reveal hitherto unknown knowledge regarding how the capability areas relate one another in these organizations. From the practical standpoint, the resulting architecture has the potential to transform capability management practices in open data organizations towards greater competitiveness through more flexibility and increased value generation. From the research point of you, this paper motivates theory development in this discipline
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Open-Source Coprocessor for Integer Multiple Precision Arithmetic
- Kamil Rudnicki
- Tomasz Stefański
- Wojciech Żebrowski
This paper presents an open-source digital circuit of the coprocessor for an integer multiple-precision arithmetic (MPA). The purpose of this coprocessor is to support a central processing unit (CPU) by offloading computations requiring integer precision higher than 32/64 bits. The coprocessor is developed using the very high speed integrated circuit hardware description language (VHDL) as an intellectual property (IP) core. Therefore, it can be implemented within field programmable gate arrays (FPGAs) at various scales, e.g., within a system on chip (SoC), combining CPU cores and FPGA within a single chip as well as FPGA acceleration cards. The coprocessor handles integer numbers with precisions in the range 64 bits–32 kbits, with the limb size set to 64 bits. In our solution, the sign-magnitude representation is used to increase the efficiency of the multiplication operation as well as to provide compatibility with existing software libraries for MPA. The coprocessor is benchmarked in factorial ( n! ), exponentiation ( nn ) and discrete Green’s function (DGF) computations on Xilinx Zynq-7000 SoC on TySOM-1 board from Aldec. In all benchmarks, the coprocessor demonstrates better runtimes than a CPU core (ARM Cortex A9) executing the same computations using a software MPA library. For sufficiently large input parameters, our coprocessor is up to three times faster when implemented in FPGA on SoC, rising to a factor of ten in DGF computations. The open-source coprocessor code is licensed under the Mozilla Public License.
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Open-source software (OSS) and hardware (OSH) in UAVs
- Paweł Burdziakowski
- Navid Razmjooy
- Vania Estrela
- Jude Hemanath
The popularity of the Open Source Tool (OST) has expanded significantly. This is the case for Unmanned Aerial Vehicles (UAVs) based on open-source hardware (OSH) as well. Open-source software (OSS) and OSH can be applied in a wide range of applications and can improve several technologies. The chapter begins with an introduction to OSS depicting its rationale, description of fundamental differences between OSS and proprietary software (PS), what benefits OSSs provide to overall UAV community, the motives leading people to pick up an OSS instead of a PS, which helps the academic and research community. This chapter also covers some OSSs used within the UAV community to support all aspects of UAV technology and the Remote Sensing (RS) and photogrammetry data post-processing chain. It is possible to build fully autonomous and operational UAV based only on OSH and OSS. The chapter describes the state of the art for OSS widely used in UAV technology, the software used in all aspects of UAV technology such as ARDUPILOT-based Autopilot firmware, MISSION PLANNER-based ground station, OPENTX transmitter software, MINIM On-Screen Data (OSD) software, Open Drone Map photogrammetry data processing suite, Web drone data-processing suite WebODM. This chapter describes several concepts and characteristics of open software/hardware, built-in functions, and particular features as well as platform requirements. A typical UAV photogrammetry workflow for drone construction with flight planning/execution and OSS data processing is provided.
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Operation of the Hybrid Photovoltaic-Battery System on the Electricity Market—Simulation, Real-Time Tests and Cost Analysis
- Robert Małkowski
- Marcin Jaskólski
- Wojciech Pawlicki
This paper presents research on a hybrid photovoltaic-battery energy storage system, declaring its hourly production levels as a member of a balancing group submitting common scheduling unit to the day-ahead market. It also discusses the variability of photovoltaic system generation and energy storage response. The major research questions were whether the operation of a hybrid photovoltaic-battery energy storage system is viable from the technical and economic viewpoint and how to size battery energy storage for that purpose. The DIgSILENT PowerFactory environment was used to develop the simulation model of postulated hybrid system. Then, tests were conducted on real devices installed in the LINTE^2 laboratory at Gdańsk University of Technology, Poland. Firstly, power generation in the photovoltaic system was modeled using hardware in the loop technique and tested in cooperation with emulated photovoltaic and real battery energy storage system (lithium-ion battery, 25 kWh). Secondly, a real photovoltaic power plant (33 kW) and real battery energy storage were applied. The results obtained from laboratory experiments showed that market operation of hybrid photovoltaic-battery energy storage system is feasible. However, developing a control strategy constitutes a great challenge, as the operator is forced to intervene more frequently than the simulation models indicate in order to keep the parameters of battery storage within accepted ranges, especially in view of a sudden weather breakdown. Levelized cost of electricity from photovoltaic-battery energy storage system varied from 314 to 455 $/MWh, which has proven to be from two to three times higher than the current annual average day-ahead market price in Poland.
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Opinia historyczno-konserwatorska o projekcie koncepcyjnym przebudowy wnętrz zabytkowego budynku centrali Banku Gospodarstwa Krajowego w Warszawie autorstwa przcowni JEMS Architekci z 2020 r. w świetle ochrony modernistycznego dziedzictwa kulturowego
- Maria Sołtysik
Opinia o projekcie koncepcyjnym przebudowy wnętrz zabytkowego budynku centrali Banku Gospodarstwa Krajowego w Warszawie autorstwa pracowni JEMS Architekci z 2020 r została wykonana w świetle ochrony modernistycznego dziedzictwa kulturowego. Opinia zawiera 6 głównych rozdziałów: 1. Informacje wstępne; 2. Główne kierunki i idee modernizmu w architekturze okresu międzywojennego; 3. Historyczne wnętrza gmachu centrali BGK - wybitne dzieło polskiego modernizmu, symbol nowoczesności Polski międzywojennej i świadectwo ważnej roli Banku w życiu gospodarczym kraju; 4. Cel konserwatorski przebudowy wnętrz gmachu BGK i rola w tym procesie współczesnego BGK jako gospodarza obiektu; 5. Specyfika ochrony dziedzictwa modernizmu i opinia dotycząca głównych wytycznych ochrony konserwatorskiej wnętrz BGK w świetle celu konserwatorskiego przebudowy; 6. Analiza projektu koncepcyjnego przebudowy wnętrz centrali BGK autorstwa JEMS Architekci pod kątem zachowania historycznego dziedzictwa materialnego i niematerialnego wnętrz BGK z lat 1928-31; 7. Podsumowanie opinii. Wykonana opinia stała się podstawą dla zasadniczej korekty pierwotnego projektu koncepcyjnego przebudowy wnętrz gmachu BGK i podstawą do wykonania realizowanego obecnie projektu budowlanego tej przebudowy.
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Opportunities and challenges for exploiting drones in agile manufacturing systems
- Mariusz Deja
- Mieczysław S. Siemiątkowski
- George-Ch. Vosniakos
- Gerasimos Maltezos
Drones have become an advanced supply chain implementation instrument, especially in connecting warehouses to outlet points or even individual customers. However, their potential application in an intra-logistics framework has not been studied, let alone explored so far. Modeling and simulations in virtual environments can help explore and evaluate the opportunities for practical and profitable applications of drones in manufacturing systems. This paper considers use of drones in replacing or supplementing industrial robots, transportation systems and humans in factories, especially regarding agile manufacturing under the requirements of flexibility, reconfigurability and collaboration. Currently available drone technology regarding positioning, navigation and communication is examined in order to define possible individual tasks and general operations that they can perform, as well as pertinent limitations. A typical scenario of a flexible manufacturing system is simulated and conceptually presented for discussing drone integration and missing links. The main issues refer to mechanical integration with machinery and parts, information integration in the manufacturing system, especially in an Industrial Internet of Things direction, scheduling and collaboration with humans and robots including safety.
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Optical sensor of a person sitting on a chair and dressed in multi-layered clothes vital signs monitoring
- Adam Bujnowski
- Mariusz Kaczmarek
- Kamil Osiński
- Michal Gramowski
- Jerzy Wtorek
An optoelectronic device enhancing a smart chair functionality is presented in the paper. Its essential purpose is a detection of a sitting person presence on the chair by means of detecting the vital signs. Additionally, it could be used for determining of clothes layer parameters useful in adjusting a system of a capacitive electrocardiography.
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Optimisation of turbine shaft heating process under steam turbine run-up conditions
- Krzysztof Dominiczak
- Marta Drosińska-Komor
- Romuald Rządkowski
- Jerzy Głuch
An important operational task for thermal turbines during run-up and run-down is to keep the stresses in the structural elements at a right level. This applies not only to their instantaneous values, but also to the impact of them on the engine lifetime. The turbine shaft is a particularly important element. The distribution of stresses depends on geometric characteristics of the shaft and its specific locations. This means a groove manufactured for fixing the rotor blades. The extreme stresses in this place occur during the start-up and the shaft heating to normal operating temperature. The process needs optimisation. Optimization tasks are multidisciplinary issues and can be carried out using different methods. In recent years, particular attention in optimisation has been paid to the use of artificial intelligence methods. Among them, a special role is assigned to genetic algorithms. The paper presents a genetic algorithm method to optimise the steam turbine shaft heating process during its start-up phase. The presented optimization task of this algorithm is to carry out the process of the shaft heating as soon as possible at the conditions of not exceeding the stresses at critical locations at any heating phase.
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OPTIMISING RIG DESIGN FOR SAILING YACHTS WITH EVOLUTIONARY MULTIOBJECTIVE ALGORITHM
- Mikołaj Pawłusik
- Rafał Szłapczyński
- Artur Karczewski
The paper presents a framework for optimising a sailing yacht rig using Multi-objective Evolutionary Algorithms and for filtering obtained solutions by means of a Multi-criteria Decision Making method. A Bermuda sloop with discontinuous rig is taken under consideration as a model rig configuration. It has been decomposed into its elements and described by a set of control parameters to form a responsive model which can be used for optimisation purposes. Considering the contradictory nature of real optimisation objectives, a multi-objective approach has been chosen to address this issue. Once the optimisation process is over, a Multi-criteria Decision Making method based on a w-dominance relation is applied for filtering out the most interesting solutions from the obtained Pareto set. The proposed method has been implemented, and selected results are provided and discussed.
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Optimization of liquid chromatographic separation of pharmaceuticals within green analytical chemistry framework
- Aysegul Dogan
- Marek Tobiszewski
The contribution is aimed at the development of methodology that allows to consider green analytical chemistry criteria during optimization of liquid chromatographic separation with design of experiment. The objectives of the optimization are maximization of peak areas of five non-steroid anti-inflammatory drugs, maximization of resolution between peaks, with simultaneous shortening of chromatographic separation time and minimization of mobile phase environmental impact. This is obtained with design of experiment to consider many experimental conditions and Derringer's desirability function to combine many optimization objectives. The possibilities of introduction different green analytical chemistry metrics are discussed and the methodology of mobile phase greenness assessment is proposed. The optimal response for all objectives is obtained for 0.96 mL min−1 of mobile phase flow rate, 61% of MeOH content, temperature of 25°C and pH equal to 4.5. The separation takes less than 9 min.
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Optimization of Stabilizing Systems in Protection of Cultural Heritage: The Case of the Historical Retaining Wall in the Wisłoujście Fortress
- Piotr Chudoba
- Jarosław Przewłócki
- Piotr Samól
- Lesław Zabuski
The aim of the paper is to propose new quantitative criteria for selecting the optimal method of securing and repairing a historical object, which take into account Structural, Conservation and Architectural aspects (the S–C–A method). Construction works on cultural heritage sites tend to be challenging and require an interdisciplinary approach. Therefore, they are strictly related to the philosophy of sustainable development which seeks adequate proportions between factors indicated on the natural and social environment. Optimization of several systems stabilizing retaining structure that are a historic object was considered in the paper. Appropriate formulas for scores meeting additional conservation and aesthetic requirements were proposed. The method is used in the stabilization of the brick retaining wall, a part of the Wisłoujście Fortress located in Gdańsk, Poland. In order to compute the displacement of the wall and its stability, numerical analysis was performed by the two-dimensional explicit Finite Difference Method (using the FLAC2D software). The algorithm proposed could be beneficial to the protection of cultural heritage since it could also be applied to other structures, such as roof trusses, masonry walls, pillars, etc.
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Optimization of Wireless Networks for Resilience to Adverse Weather Conditions
- Michał Pióro
- Emma Fitzgerald
- Ilya Kalesnikau
- Dritan Nace
- Jacek Rak
In this chapter, we consider how adverse weather conditions such as rain or fog affect the performance of wireless networks, and how to optimize these networks so as to make them robust to these conditions. We first show how to analyze the weather conditions in order to make them useful for network optimization modelling. Using an example realistic network, we show how to optimize two types of wireless networks: free-space optical (FSO) networks and wireless mesh networks (WMN). The key difference between the two network types is that in WMNs, links interfere with each other, while in FSO networks, link rates may be assumed independent. We formulate optimization problems to protect each network type against adverse weather conditions, discuss solution methods to solve them and present a numerical study illustrating the considerations of the chapter.
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Optimized Space-Vector Modulation Schemes for Five-Phase Precision Low-Speed Drives with Minimizing the Stator Current Ripple
- Valentin Tomasov
- Aleksander Usoltsev
- Denis Vertegel
- Paweł Szczepankowski
- Ryszard Strzelecki
- Nikolai Poliakov
One of the main ways to improve the quality of a precision electric drive is minimization of the stator current pulsations generated by the voltage inverter. The solution of this problem can be achieved by using of multiphase inverters, as well as improving control algorithms. This paper considers the influence of the space-vector modulation algorithm with different switching sequences of basic vectors on the stator current pulsations generated by the five-phase voltage inverter.
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Optymalizacja prędkości obrotowej narzędzia podczas frezowania przedmiotów wielkogabarytowych
- Krzysztof Kaliński
- Marek Galewski
- Michał Mazur
- Natalia Stawicka-Morawska
Przedstawiono nową metodę wyznaczania optymalnej prędkości obrotowej narzędzia podczas frezowania przedmiotów wielkogabarytowych. Parametry modelu obliczeniowego (modalnego) przedmiotu obrabianego są wyznaczane z wykorzystaniem jedynie eksperymentalnej analizy modalnej. To ostatnie umożliwia eliminację pracochłonnego etapu modelowania przedmiotu, jakim jest stosowane dotychczas tworzenie i walidacja modelu MES. Otrzymany w ten sposób model jest następnie wykorzystywany do symulacji procesu obróbkowego. Ponadto, podczas symulacji uwzględniany jest model obliczeniowy wirującego narzędzia oraz przyjęty model dynamiki procesu skrawania. Skuteczność metody potwierdzono na podstawie wyników badań eksperymentalnych procesu.
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Orbital blowout trauma occurring at the workplace – clinical, biomechanical and legal aspects
- Andrzej Skorek
- Paweł Kłosowski
- Krzysztof Żerdzicki
- Piotr Skorek
- Paweł Lemski
- Marcin Zmuda Trzebiatowski
Introduction and objective: Craniofacial injury at the workplace may lead to orbital blowout fractures. The aim of the study is the development of own numerical model of the eye orbit, assessment of the damage zones, and comparing them with clinical examinations. In addition, the current legal status of patients after injuries is presented Material and methods: In laboratory tests performed on bones collected from the upper and medial orbital wall (examination on fresh corpses), the Young’s modulus was determined for these bones. Based on the CT image, a numerical model of the eye orbit was created. The damage zones within the eye socket were assessed after a blow (dynamic model) to the inferior and lateral walls, and only to the inferior wall. Comparative clinical material were 9 patients with orbital blowout fracture treated at the Clinic of Otolaryngology Results: Experiment 1: the damage zone covered an area of 0.54cm2, and was located medially and laterally from the infraorbital nerve canal. Experiment 2: the damage zone was smaller – 0.38 cm2, and located medially to the infraorbital nerve canal. The results obtained in the experiment were compared with the CT image of the eye sockets of patients after injuries. On this basis, presumptions were made concerning the mechanism of the trauma. Conclusions: The finite element method is a good tool for assessing the pathomechanism of trauma, as well as for an attempt to determine the circumstances of the event. Based on analysis of the numerical and clinical images, the necessity for using protective measures which absorb the impact to the inferior wall and temporal areas should be emphasised, as well as the fact that using merely goggles is insufficient protection of the eye orbit.
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Organisational Competence vs Transferability of Knowledge in Cluster Organisations and Technology Parks
- Anna Lis
- Jolanta Žemgulienė
Purpose. The main paper aims to evaluate the impact of organisational competence on knowledge and information flows within cluster organisations and technology parks, with particular emphasis on innovative content knowledge. The paper addresses the research question: “What set of competencies of cooperating companies allows access to information and knowledge in cluster and parks structures?" Methodology. The authors report their findings from a quantitative study carried out in four cluster organisations and three technology parks functioning in Poland. The research sample covered a total of 269 enterprises: 132 cluster members and 137 park tenants. The primary method of data collection was a survey questionnaire. Data analysis was conducted using the interdependence of variables, ANOVA, and logistic regression. Results. The research showed that the surveyed enterprises from both analysed groups preferred cooperation with partners of a similar level of competence development and the same or complementary scope of competence. This set of competencies of cooperating organisations also guaranteed better access to information and knowledge resources, including confidential information and new knowledge. This study additionally indicated that the knowledge creation activities performed by the cooperating cluster organisations depended on the proximity of the competencies of organisations as well as on the nature of the information, disseminated within the cluster organisations. The theoretical contribution. The theoretical contribution is related to the results obtained by analysing the phenomenon of information and knowledge dissemination in cluster and park structures, revealing the impact made by the competence proximity of cooperating organisations on the access to this such resources. Thus, the findings supplement the state-of-the-art knowledge of the concept of industrial clusters by presenting a broader view on cooperation developed in geographical proximity, based on a set of various partner competencies.
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Organizacja systemu opieki nad seniorami wyzwaniem dla samorządów lokalnych
- Anita Richert-Kaźmierska
A significant part of the activities undertaken so far under the senior policy, also at the local level, have been focused on seniors’ social (physical and educational) activation. The growing number of the oldest seniors, with limited independence, living alone in single‑person households, away from their families, will force the policy priorities to be reoriented in such a way as to develop efforts to provide different types of support and care for older citizens. The results of research carried out by different researchers confirm that the system of care for seniors with independence restrictions, based mainly on the family members support, is no longer applicable. However, finding a good solution in new conditions will be extremely difficult. First of all, due to the seniors’ preferences (the desire to spend old age in their own home, in familiar surroundings), social conditions and family relationships (singularization in old age, loosening family and social relationships, transferring social relationships into the virtual sphere inaccessible for many seniors), labor market situation (staff deficit in the care system) and public finances (the need to rationalize the growing public expenditure related to the provision of health and care services). The aim of the article is to present selected aspects of seniors’ care system organization in Poland in local territorial units’ perspective. In the article author presents the results of literature analysis of seniors’ care system in Poland, discusses the results of an interview conducted among the seniors of one of the Pomeranian communes regarding availability of care from the closest family members, as well as proposes the concept of organizing the local care system for seniors
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Organizational Wisdom: The Impact of Organizational Learning on the Absorptive Capacity of an Enterprise
- Agata Pierścieniak
- Monika Stelmaszczyk
Purpose: In this article, we analyze the concept of organizational wisdom, indicating its key elements and verifieng the relationships between them. Design/Methodology/Approach: The study was conducted at Vive Textile Recycling Sp. z o.o in Poland. Empirical data was collected from 138 managers using the PAPI technique. Structural equation modelling (SEM) was performed to test the research hypotheses. Additionally, the significance of indirect effects was checked, using the bootstrap method. Findings: Our findings show that organizational wisdom can, from the perspective of management sciences, be considered as a configuration of two elements: organizational learning and absorptive capacity. Our analysis shows that exploitative organizational learning plays an important role in shaping both potential and realized absorptive capacity. Exploratory organizational learning, in contrast, only affects the realized absorptive capacity. Practical Implications: Our research in practice will allow managers to understand that for the company to successfully achieve its goals, considering the changing environment, it should show organizational wisdom. To shape the ability to acquire, assimilate, transform, and make use of valuable external knowledge, they ought to rely on procedures (processes, databases, competences, etc.) that they know well. Their recent procedures or processes will only be capable of influencing their ability to transform and apply external knowledge. Originality/Value: The value of our research is drawing attention to the categories of organizational wisdom, which is not often analyzed in management sciences. The originality of our considerations consists in our attempt to describe the phenomenon not only by indicating its main elements, but also by establishing the relationship between them.
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Oscylacyjna metoda oceny oporu toczenia opon samochodowych na nawierzchniach drogowych o różnej teksturze i sztywności
- Wojciech Owczarzak
Opór toczenia jest jednym z trudniejszych do wyznaczenia parametrów opon samochodowych. Jest to spowodowane tym, iż w przypadku nowoczesnych opon siła oporu toczenia odpowiada 0,5–1% obciążenia opony, dlatego pomiary bardzo małych sił muszą być wykonywane w silnie obciążonym układzie. Stanowi to ogromny problem, szczególnie w warunkach drogowych. Pomiary laboratoryjne są łatwiejsze do wykonania, ze względu na możliwość kontrolowania warunków otoczenia, jednakże w większości przypadków maszyny bieżne nie mogą być wyposażone w prawdziwe nawierzchnie drogowe. Zazwyczaj są to stalowe bębny lub w najlepszym wypadku bębny pokryte replikami nawierzchni. Niniejsza rozprawa doktorska opisuje laboratoryjną metodę oceny oporu toczenia, którą można zastosować do wstępnej oceny nawierzchni drogowych (na podstawie małych próbek nawierzchni) oraz opon. Metoda opiera się na pośrednim pomiarze strat energetycznych występujących w wyniku cyklicznego dociskania opony do nawierzchni, wymuszonego swobodnym spadaniem powodującym oscylacje układu zawierającego masę, sprężystość i tłumienie.
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Otopy Classification of Gradient Compact Perturbations of Identity in Hilbert Space
- Piotr Bartłomiejczyk
- Piotr Nowak-Przygodzki
We prove that the inclusion of the space of gradient local maps into the space of all local maps from Hilbert space to itself induces a bijection between the sets of the respective otopy classes of these maps, where by a local map we mean a compact perturbation of identity with a compact preimage of zero.
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Outsourcing w wybranych podmiotach leczniczych województwa pomorskiego.
- Mateusz Muchlado
Celem badawczym, przyjętym w niniejszej pracy jest identyfikacja procesów zlecanych na zewnątrz w badanej populacji wraz z czynnikami warunkującymi ich skuteczność. Celem utylitarnym jest opracowanie narzędzia umożliwiającego dobór dostawców oraz ocenę procesów poddanych outsourcingowi. W rozdziale pierwszym pracy omówiono pojęcie outsourcingu oraz jego wykorzystanie w zarządzaniu procesami organizacji. Zidentyfikowano również czynniki wpływające na to, że organizacje decydują się na zlecanie procesów na zewnątrz. Przedstawiono również aktualne metody oceny skuteczności procesów. W rozdziale drugim przedstawiono charakterystykę podmiotu badań oraz wnioski z przeglądu literatury dotyczącej outsourcingu w podmiotach leczniczych w Polsce i za granicą. Zaprezentowano również i poddano krytycznej analizie istniejące już modele oceny skuteczności outsourcingu oraz odpowiednie uwarunkowania prawne i normatywne. W rozdziale trzecim opisano zastosowaną metodykę badań, w tym hipotezy sformułowane na podstawie studium literatury przedmiotu. Zawarto tu też wyniki badań ilościowych oraz jakościowych, które posłużyły do weryfikacji hipotez. Przedstawione zostały procesy zlecane na zewnątrz przez badane podmioty wraz z czynnikami warunkującymi skuteczność tych procesów. Przedstawiono również arkusz oceny dostawcy outsourcingowego, który jest wynikiem nawiązującym do celu utylitarnego niniejszej pracy. W podsumowaniu zawarto ujęte syntetycznie rezultaty przeprowadzonych badań, wnioski i rekomendacje oraz ograniczenia dotyczące wyników tej pracy.
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Oversizing the photovoltaic generator capacity in a micro photovoltaic plant
- Zbigniew Lubośny
A significant part of photovoltaic micro installations in Poland is characterized by photovoltaic generator oversizing in relation to the inverter. The idea of oversizing, however, still raises doubts among some plant owners. In the paper, the energy yield of installation with an oversized and not oversized photovoltaic generator is presented on selected examples, showing the legitimacy of oversizing.
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Overview of the three multicriteria approaches applied to a global assessment of analytical methods
- Paweł Mateusz Nowak
- Paweł Kościelniak
- Marek Tobiszewski
- Ana Ballester-Caudet
- Pilar Campíns-Falcó
Critical and global evaluation of analytical methods should be one of the primary goals in analytical chemistry. A holistic approach, however, requires a look at the varied features: commonly discussed validation criteria, often underrated practical and economic aspects, and typically overlooked compliance with the principles of green analytical chemistry. Carrying out such an assessment in a critical and transparent way is extremely difficult without special tools. The purpose of this work is to discuss and compare the three different approaches that seem to be potential candidates: multi-criteria decision analysis methods (MCDA), HEXAGON, and RGB model. The basic principles of each methodology, individual possibilities offered, and the results of the assessment of selected model methods will be presented. Ultimately, the potential compatibility of assessing the same group of methods using different tools will be examined. This contribution can help to select optimal tool and conduct more thorough and insightful assessments.
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Oznaczenie rtęci w tytoniu cygarowym jako wyzwanie analityczne
- Paweł Hać
- Bartłomiej Cieślik
- Piotr Konieczka
Przed wybuchem pandemii COVID-19 obserwowano wyraźny i systematyczny wzrost rynku cygarowego, a co za tym idzie, również i grona cigar aficionado, czyli miłośników cygar. W pracy poruszono tematykę zawartości rtęci w cygarach i przedstawiono wyniki przeprowadzonych badań. Z racji wielu podobieństw porównano ją z zawartością tego pierwiastka w tytoniu papierosowym. Stężenie Hg w tytoniu papierosowym na przestrzeni kilkudziesięciu lat wyraźnie spadło. Analizując literaturę zauważyć można, że stężenie rtęci w cygarach jest większe aniżeli w papierosach, od czego odbiegają wyniki przeprowadzonych badań własnych. Większość uzyskanych stężeń mieści się w zakresie odpowiadającemu tytoniowi papierosowemu z przytaczanych prac, choć niektóre wartości są nawet kilkukrotnie wyższe. Przyczyny tego doszukiwać się można najprawdopodobniej w ewentualnym stosowaniu środków ochrony roślin lub nawozów zawierających rtęć.
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Paenibacillus alvei MP1 as a Producer of the Proteinaceous Compound with Activity against Important Human Pathogens, Including Staphylococcus aureus and Listeria monocytogenes
- Magdalena Pajor
- Zirui Ray Xiong
- Randy Worobo
- Piotr Szweda
An emerging need for new classes of antibiotics is, on the one hand, evident as antimicrobial resistance continues to rise. On the other hand, the awareness of the pros and cons of chemically synthesized compounds’ extensive use leads to a search for new metabolites in already known reservoirs. Previous research showed that Paenibacillus strain (P. alvei MP1) recovered from a buckwheat honey sample presented a wide spectrum of antimicrobial activity against both Gram-positive and Gram-negative pathogens. Recent investigation has confirmed that P. alvei MP1 (deposited at DDBJ/ENA/GenBank under the accession WSQB00000000) produces a proteinaceous, heat-stable compound(s) with the maximum antimicrobial production obtained after 18 h of P. alvei MP1 growth in LB medium at 37 °C with continuous shaking at 200 RPM. The highest activity was found in the 40% ammonium sulfate precipitate, with high activity also remaining in the 50% and 60% ammonium sulfate precipitates. Moderate to high antimicrobial activity that is insensitive to proteases or heat treatment, was confirmed against pathogenic bacteria that included L. monocytogenes FSL – X1-0001 (strain 10403S), S. aureus L1 – 0030 and E. coli O157: H7. Further studies, including de novo sequencing of peptides by mass spectrometry, are in progress
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Paired domination subdivision and multisubdivision numbers of graphs
- Joanna Raczek
- Magda Dettlaff
The paired domination subdivision number sdpr(G) of a graph G is the minimum number of edges that must be subdivided (where an edge can be subdivided at most once) in order to increase the paired domination number of G. We prove that the decision problem of the paired domination subdivision number is NP-complete even for bipartite graphs. For this reason we define the paired domination muttisubdivision number of a nonempty graph G, denoted by msdpr(Cr), as the minimum positive integer k such that there exists an edge which must be subdivided k times to increase the paired domination number of G. We show that msdpr(Gr) < 4 for any graph G with at least one edge. We also determine paired domination multisubdivision numbers for some classes of graphs. Moreover, we give a constructive characterizations of all trees with paired domination multisubdivision number equal to 4.
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PARAMETERS OF THE ELECTROPHORETIC DEPOSITION PROCESS AND ITS INFLUENCE ON THE MORPHOLOGY OF HYDROXYAPATITE COATINGS. REVIEW
- Aleksandra Laska
- Michał Bartmański
Metallic materials intended for bone implants should exhibit not only appropriate mechanical properties, but also high biocompatibility. The surface treatment modifications, for example acidic treatment, laser treatment, ion implantation and deposition of highly biocompatible coatings, are practiced. One of the most popular methods of surface modification is to deposit hydroxyapatite (HAp) coatings. HAp naturally occurs in human body, but can be also synthesized in laboratory conditions. Among diverse deposition techniques, electrophoretic deposition (EDP) is a cost-effective method in which charged particles, dispersed in an organic medium, after applying voltage migrate to the counter charged electrode forming a thin coating. There are several parameters that can be controlled during the process and that directly affect the morphology of the surface. The zeta potential and pH of prepared colloidal suspension are closely related to suspension stability and affect the susceptibility for agglomeration of the particles. Electrical settings, especially applied voltage, affect primarily the mass of deposition, but also the porosity of the coating, as well as its homogeneity. One of the basic parameters of EDP method is time of process. With increasing process time, the thickness of the deposited coating increases. Importantly, its mechanical properties also decrease. Moreover, the particles shape and size also affect the morphology of the deposited coating. The analysis of many variables is necessary to choose the right parameters to obtain the coating with desired morphology. In this paper, the influence of each parameter on the morphology of hydroxyapatite coatings is discussed.
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Parametric method applicable in assessing breakout force and time for lifting slender bodies from seabed
- Jan Michalski
The article presents a parametric method applicable in assessing the suction force of a slender body to the seabed, and prognosing the body extrication time. Along with the body weight in water, the information on the suction force is essential for assessing the force needed to lift the object from the seabed. Based on the Foda theory and the resulting integral equation, which relates the maximum suction force with basic parameters of the issue of concern, the parametric method has been developed which can be widely applied in engineering practice of lifting objects. A set of discrete values of parameters selected from the range of typical values for engineering practice was the basis for developing algebraic formulas approximating the integral Foda equation for slender bodies. The included results of tests present the variability of suction force characteristics and the envelopes of maximum forces needed to extricate the body from the seabed.
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Parametric optimization of sandwich composite footbridge with U-shaped cross-section
- Tomasz Ferenc
- Tomasz Mikulski
Parametric optimization of sandwich composite footbridge was presented in the paper. Composite footbridge has 14,5 m long and has U-shaped cross-section with inner dimensions 2,6 × 1,3 m. The sandwich structure in made from GFRP laminate as a faces and PET foam as a core. The aim of analysis was to minimize the mass of the new footbridge that can lead to minimize the cost of structure. After optimization was conducted, the new structure was compare with the realized one. The results show that while mass can be decreased the state variables of structure like maximum displacement, strain or natural frequency do not change significantly. Moreover, results show that, although the mass is decreased, stiffness of the new structure is even higher. Optimization and sensitivity analysis, the divisions of theory of designing, provide the designer a significant support. Despite presented optimization, also sensitivity analysis can additionally be effectively used in issues related to strengthening or modernizing structures as well as in the process of identifying quantities describing the computational model.
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Parametric Study on a Performance of a Small Counter-Rotating Wind Turbine
- Michał Pacholczyk
- Dariusz Karkosiński
A small Counter-Rotating Wind Turbine (CRWT) has been proposed and its performancehas been investigated numerically. Results of a parametric study have been presented in this paper.As parameters, the axial distance between rotors and a tip speed ratio of each rotor have been selected.Performance parameters have been compared with reference to a Single Rotor Wind Turbine (SRWT).Simulations were carried out with Computational Fluids Dynamics (CFD) solver and a Large EddyScale approach to model turbulences. An Actuator Line Model has been chosen to represent rotors inthe computational domain. Summing up the results of simulation tests, it can be stated that whenconstructing a CRWT turbine, rotors should be placed at a distance of at least 0.5 D (where D is rotorouter diameter) or more. One can then expect a noticeable power increase compared to a singlerotor turbine. Placing the second rotor closer than 0.5 D guarantees a significant increase in power, butin such configurations, dynamic interactions between the rotors are visible, resulting in fluctuationsin torque and power. Dynamic interactions between rotor blades above 0.5 D are invisible.
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Particle swarm optimization algorithms for autonomous robots with deterministic leaders using space filling movements
- Doina Logofătu
- Gil Sobol
- Christina Andersson
- Daniel Stamate
- Kristiyan Balabanov
- Tymoteusz Cejrowski
In this work the swarm behavior principles of Craig W. Reynolds are combined with deterministic traits. This is done by using leaders with motions based on space filling curves like Peano and Hilbert. Our goal is to evaluate how the swarm of agents works with this approach, supposing the entire swarm will better explore the entire space. Therefore, we examine different combinations of Peano and Hilbert with the already known swarm algorithms and test them in a practical challenge for the harvesting of manganese nodules on the sea ground with the use of autonomous agents. We run experiments with various settings, then evaluate and describe the results. In the last section some further development ideas and thoughts for the expansion of this study are considered.
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Partycypacja obywatelska młodzieży w opinii gmin polskich na przykładzie projektu South Baltic Youth Core Group Network
- Krystyna Gomółka
- Izabela Borucińska
Celem badań było ukazanie partycypacji obywatelskiej młodzieży w opinii gmin polskich na przykładzie projektu South Baltic Youth Core Group Network
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Path Loss Analysis for the IoT Applications in the Urban and Indoor Environments
- Piotr Rajchowski
- Jarosław Sadowski
- Olga Błaszkiewicz
- Krzysztof Cwalina
- Alicja Olejniczak
The Internet of Things (IoT) networks concept implies their presence in a various and untypical locations, usually with a disturbed radio signals propagation. In the presented paper an investigation of an additional path loss observed in an underground environment was described. The proposed measurement locations correspond to the operation areas of rapidly growing narrowband IoT (NBIoT) networks, the ones using the Long Term Evolution (LTE) network resources. During the measurement campaign the received signal power (RSP) in an outdoor-to-indoor (OUT2IN) and outdoor-to-outdoor radio link was measured. After analysis of the measurement results obtained in the building floors and in a basement, it was possible to derive an assessment of the observed additional 11.4 dB - 18.3 dB attenuation of the RSP in the outdoor-to-basement communication regarding the typical signal reception on a building floor (OUT2IN).
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Pathogenesis of psoriasis in the “omic” era. Part II. Genetic, genomic and epigenetic changes in psoriasis
- Bogusław Nedoszytko
- Aneta Szczerkowska-Dobosz
- Marta Stawczyk-Macieja
- Agnieszka Owczarczyk-Saczonek
- Adam Reich
- Joanna Bartosińska
- Aleksandra Batycka-Baran
- Rafał Czajkowski
- Iwona T. Dobrucki
- Lawrence W. Dobrucki
- Magdalena Górecka-Sokołowska
- Anna Janaszak-Jasiecka
- Leszek Kalinowski
- Dorota Krasowska
- Dorota Purzycka-Bohdan
- Adrianna Radulska
- Edyta Reszka
- Dominik Samotij
- Marta Sobalska-Kwapis
- Andrzej Słominski
- Dominik Strapagiel
- Justyna Szczęch
- Michał Żmijewski
- Roman J. Nowicki
- Michal Zmijewski
Psoriasis is a multifactorial disease in which genetic, environmental and epigenetic factors regulating gene expression play a key role. In the “genomic era”, genome-wide association studies together with target genotyping platforms performed in different ethnic populations have found more than 50 genetic susceptible markers associated with the risk of psoriasis which have been identified so far. Up till now, the strongest association with the risk of the disease has been proved for HLA-C*06 gene. The majority of other psoriasis risk SNPs are situated near the genes encoding molecules involved in adaptive and innate immunity, and skin barrier function. Many contemporary studies indicate that the epigenetic changes: histone modification, promoter methylations, long non-coding and micro-RNA hyperexpression are considered as factors contributing to psoriasis pathogenesis as they regulate abnormal keratinocyte differentiation and proliferation, aberrant keratinocytes - inflammatory cells communication, neoangiogenesis and chronic inflammation. The circulating miRNAs detected in the blood may become specific markers in the diagnosis, prognosis and response to the treatment of the disease. The inhibition of expression in selected miRNAs may be a new promising therapy option for patients with psoriasis.
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Pathogenesis of psoriasis in the “omic” era. Part III. Metabolic disorders, metabolomics, nutrigenomics in psoriasis
- Agnieszka Owczarczyk-Saczonek
- Dorota Purzycka-Bohdan
- Bogusław Nedoszytko
- Adam Reich
- Aneta Szczerkowska-Dobosz
- Joanna Bartosińska
- Aleksandra Batycka-Baran
- Rafał Czajkowski
- Iwona T. Dobrucki
- Lawrence W. Dobrucki
- Magdalena Górecka-Sokołowska
- Anna Janaszak-Jasiecka
- Leszek Kalinowski
- Dorota Krasowska
- Adrianna Radulska
- Edyta Reszka
- Dominik Samotij
- Andrzej Słominski
- Radomir Słominski
- Marta Sobalska-Kwapis
- Marta Stawczyk-Macieja
- Dominik Strapagiel
- Justyna Szczęch
- Michał Żmijewski
- Roman J. Nowicki
Psoriasis is a systemic disease that is strictly connected with metabolic disorders (insulin resistance, atherogenic dyslipidemia, arterial hypertension, and cardiovascular diseases). It occurs more often in patients with a more severe course of the disease. Obesity is specially an independent risk factor and it is associated with a worse treatment outcome because of the high inflammatory activity of visceral fatty tissue and the production of inflammatory me - diators involved in the development of both psoriasis and metabolic disorders. However, in psoriasis the activation of the Th17/IL-17 and the abnormalities in the Th17/Treg balance axis are observed, but this pathomechanism does not fully explain the frequent occurrence of metabolic disorders. Therefore, there is a need to look for better biomarkers in the diagnosis, prognosis and monitoring of concomitant disorders and therapeutic effects in psoriasis. In addition, the education on the use of a proper diet as a prophylaxis for the development of the above disorders is an important element of holistic care for a patient with psoriasis. Diet may affect gene expression due to epigenetic modification which encompasses interactions of environment, nutrition and diseases. Patients with psoriasis should be advised to adopt proper diet and dietician support.
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Peptide dendrimers as antifungal agents and carriers for potential antifungal agent—N3‐(4‐methoxyfumaroyl)‐(S)‐2,3‐ diaminopropanoic acid—synthesis and antimicrobial activity
- Magdalena Stolarska
- Katarzyna Gucwa
- Zofia Urbańczyk-Lipkowska
- Ryszard Andruszkiewicz
A series of peptide dendrimers and their conjugates with antimicrobial agent FMDP (N3‐(4‐methoxyfumaroyl)‐(S)‐2,3‐diamino‐propanoic acid) were synthesized. The obtained compounds were tested for the antibacterial and antifungal activity. All novel dendrimers displayed much better activity against the tested strains than FMDP itself. Moreover, their conjugates with FMDP also exhibited antimicrobial activity. The most promising molecules were tested against a broad selection of fungal strains. The analysis of their antifungal properties indicates that the examined molecules are efficient growth inhibitors of fluconazole‐resistant hospital‐acquired strains. Moreover, an application of amphiphilic branched peptides such as FMDP carriers suggests that transport mechanism involves more likely the cell membrane perturbation than the mediation of the specific transport proteins. The activity of obtained compounds strongly depends on the specific structure of the molecule.
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Perceptual and Motor Effects of Muscle Co-activation in a Force Production Task
- Cristian Cuadra
- Wiktoria Wojnicz
- Mark Latash
- Ziga Kozinc
We tested several predictions of the theory of motor control with spatial referent coordinates related to effects of muscle coactivation on force production and perception. In particular, we predicted that subjects would produce unintentional force increase by finger flexors and be unaware of this force increase. Healthy subjects performed steady force production task in isometric conditions with visual feedback on the force level. They coactivated muscles of the arm trying to keep the force constant in the absence of visual feedback. This led to a consistent force increase not perceived by the subjects as reflected by their verbal reports. In contrast, when asked to match the force with the contralateral hand, adequate force matching was observed. Using the ‘‘inverse piano” apparatus confirmed no change in the referent coordinate of the fingers and an increase in its apparent stiffness. The results confirm the earlier hypothesis on the reciprocal command being hierarchically higher than the coactivation command. The observations suggest that verbal reports and force matching use different neural mechanisms of force perception; the former are dominated by sense of effort, which reflects primarily the magnitude of the reciprocal command. There were only minor differences between the dominant and non-dominant hands, likely reflecting the faster unintentional drifts of control variables in the dominant hand.
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Performance Analysis of Convolutional Neural Networks on Embedded Systems
- Łukasz Grzymkowski
- Tomasz Stefański
Machine learning is no longer confined to cloud and high-end server systems and has been successfully deployed on devices that are part of Internet of Things. This paper presents the analysis of performance of convolutional neural networks deployed on an ARM microcontroller. Inference time is measured for different core frequencies, with and without DSP instructions and disabled access to cache. Networks use both real-valued and complex-valued tensors and are tested using different inference engines. We conclude that the system must be tuned in a holistic way to achieve optimal efficiency.
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Performance of isotropic constitutive laws in simulating failure mechanisms in scaled RC beams
- Ireneusz Marzec
- Jerzy Bobiński
Results of numerical calculations of reinforced concrete (RC) beams are presented. Based on experimental results on longitudinally reinforced specimens of different sizes and shapes are investigated. Four different continuum constitutive laws with isotropic softening are used: one defined within continuum damage mechanics, an elasto-plastic with the Rankine criterion in tension and the Drucker-Prager criterion in compression, a formulation coupling elasto-plasticity and damage mechanics and the concrete damaged plasticity (CDP) model implemented in Abaqus. In a softening regime, a non-local theory of integral format is applied to the first three constitutive laws. A fracture energy approach is utilised in CDP model. An ability to reproduce different failure mechanisms observed in experiments for each constitutive model is analysed. A comparison of force-displacement curves and crack patterns between numerical and experimental outcomes is performed.
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Performance of organic coatings upon cyclic mechanical load
- Michał Szociński
- Kazimierz Darowicki
A number of engineering structures fail due to the fatigue damage resulting from cyclic mechanical stress. However, as far as organic coatings are concerned this degradation factor remains underestimated. In the paper the authors propose a methodology combining global electrochemical impedance spectroscopy and local atomic force microscopy measurements for evaluation of coating resistance to an impact of repetitive mechanical stress. Typical epoxy coating designated for ship hull protection has been tested in as-received state as well as after preexposure to elevated temperature. Application of atomic force microscopy-based approach helped to reveal and spatially localize the spots of organic coating degradation onset. The mechanism and process of defect formation and propagation has been shown on a microscopic scale.
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Performance-Driven Surrogate Modeling of High-Frequency Structures
- Sławomir Kozieł
- Anna Pietrenko-Dąbrowska
The development of modern high-frequency structures, including microwave and antenna components, heavily relies on full-wave electromagnetic (EM) simulation models. Notwithstanding, EM-driven design entails considerable computational expenses. This is especially troublesome when solving tasks that require massive EM analyzes, parametric optimization and uncertainty quantification be-ing representative examples. The employment of fast replacement models, also referred to as surrogates, has been fostered as a way of mitigating these issues. Unfortunately, conventional modeling meth-ods are of limited applicability for handling nonlinear outputs of high-frequency devices. The reason is the curse of dimensionality but also a fundamental requirement that design-ready surrogates are to cover wide ranges of the system parameters and its operating con-ditions. This book offers a different methodological perspective on modeling of high-frequency structures, specifically, the concept and implementation of constrained or performance-driven surrogates. The presented approach addresses the issues of dimensionality and parameter ranges through appropriate confinement of the model do-main, focused on the regions that are promising from the point of view of the relevant design objectives. The performance-driven par-adigm enables the construction of reliable surrogates at a fraction of cost required by conventional methods, and to accomplish the mod-eling tasks where other techniques routinely fail. The book provides a broad selection of specific frameworks, extensively illustrated us-ing examples of real-world microwave and antenna structures. Ap-plications, including parametric optimization and multi-objective de-sign, are also discussed, along with the exposition of inverse model-ing methods. Furthermore, the book contains introductory material on data-driven and physics-based surrogates. Practical aspects of high-frequency surrogate modeling and recommendations concern-ing particular techniques are discussed as well.
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Performance/energy aware optimization of parallel applications on GPUs under power capping
- Adam Krzywaniak
- Paweł Czarnul
In the paper we present an approach and results from application of the modern power capping mechanism available for NVIDIA GPUs to the bench- marks such as NAS Parallel Benchmarks BT, SP and LU as well as cublasgemm- benchmark which are widely used for assessment of high performance computing systems’ performance. Specifically, depending on the benchmarks, various power cap configurations are best for desired trade-off of performance and energy con- sumption. We present two: both energy savings and performance drops for same power caps as well as a normalized performance-energy consumption product. It is important that optimal configurations are often non-trivial i.e. are obtained for power caps smaller than default and larger than minimal allowed limits. Tests have been performed for two modern GPUs of Pascal and Turing generations i.e. NVIDIA GTX 1070 and NVIDIA RTX 2080 respectively and thus results can be useful for many applications with profiles similar to the benchmarks executed on modern GPU based systems.
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Person Tracking in Ultra-Wide Band Hybrid Localization System Using Reduced Number of Reference Nodes
- Piotr Rajchowski
- Jacek Stefański
- Jarosław Sadowski
- Krzysztof Cwalina
In this article a novel method of positional data integration in an indoor hybrid localization system combining inertial navigation with radio distance measurements is presented. A point of interest is the situation when the positional data and the radio distance measurements are obtained from less than thee reference nodes and it is impossible to unambiguously localize the moving person due to undetermined set of positional equations. The presented method allows to continuously provide localization service even in areas with disturbed propagation of the radio signals. Authors performed simulation and measurement studies of the proposed method to verify the precision of position estimation of a moving person in an indoor environment. It is worth noting that to determine the simulation parameters and realize the experimental studies the hybrid localization system demonstrator was developed, combining inertial navigation and radio distance measurements. In the proposed solution, results of distance measurements taken to less than three reference nodes are used to compensate the drift of the position estimated using the inertial sensor. In the obtained simulation and experimental results it was possible to reduce the localization error by nearly 50% regarding the case when only inertial navigation was used, additionally keeping the long term root mean square error at the level of ca. 0.50 m. That gives a degradation of localization precision below 0.1 m with respect to the fusion Kalman filtration when four reference nodes are present.
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Perspektywa jakości w szkolnictwie wyższym. O modelu QualHE
- Piotr Grudowski
Kategoria jakości w szkolnictwie wyższym, choć tak ważna dla zapewnienia oczekiwanego tempa rozwoju państw i społeczeństw, ciągle jeszcze nie znajduje odpowiadającego jej randze odzwierciedlenia w pracach przedstawiających tę problematykę w sposób holistyczny, w odniesieniu do stale zmieniających się możliwości i wyzwań. Oddawana do rąk Czytelników monografia wnosi wkład w wypełnianie wspomnianej luki, przede wszystkim poprzez: • przedstawienie szerokiego kontekstu ogólnoświatowego dyskursu dotyczącego kategorii jakości w szkolnictwie wyższym w ujęciu teoriopoznawczym i w wynikach badań empirycznych; • określenie potencjału i uwarunkowań aplikacyjnych dotyczących takich koncepcji jak TQM Lean Management, Six Sigma czy Lean Six Sigma; • przedstawienie aktualnych trendów w zarządzaniu usługami publicznymi jako zbioru impulsów do zmian oraz tła dla projakościowej transformacji uczelni; • wskazanie możliwości wykorzystania opracowanych przez ISO najnowszych normatywnych systemów zarządzania; • zaakcentowanie roli kultury jakości jako elementu determinującego powodzenie wszelkich inicjatyw związanych z doskonaleniem procesów uczelni; • przedstawienie wyników kompleksowych badań interesariuszy polskiego systemu szkolnictwa wyższego na temat całokształtu projakościowych regulacji i zmian w uczelniach; • odniesienie perspektyw i wyzwań dotyczących zmian w szkolnictwie wyższym do koncepcji Przemysłu 4.0 i Jakości 4.0. Zaproponowany w książce oryginalny model systemu zarządzania jakością na uczelni – QualHE – odnosi się do wymienionych elementów, pokazując ich wzajemne relacje i dynamiczny charakter. Książka jest adresowana do badaczy zainteresowanych funkcjonowaniem systemów szkolnictwa wyższego, uczelni i poszczególnych jednostek organizacyjnych oraz kierunkami ich modernizacji. Powinna też spotkać się z zainteresowaniem praktyków – przedstawicieli kadry kierowniczej oraz pracowników działów jakości, coraz powszechniej tworzonych w strukturach uczelni. Może także stanowić kompendium wiedzy i inspirację do identyfikacji działań związanych z doskonaleniem organizacji dla osób reprezentujących różne grupy interesariuszy szkół wyższych, np. studentów, absolwentów, pracowników uczelni czy pracodawców.
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Phage therapy as a novel strategy in the treatment of urinary tract infections caused by E. coli
- Beata Zalewska-Piątek
- Rafał Piątek
Urinary tract infections (UTIs) are regarded as one of the most common bacterial infections affecting millions of people, in all age groups, annually in the world. The major causative agent of complicated and uncomplicated UTIs are uropathogenic E. coli strains (UPECs). Huge problems with infections of this type are their chronicity and periodic recurrences. Other disadvantages that are associated with UTIs are accompanying complications and high costs of health care, systematically increasing resistance of uropathogens to routinely used antibiotics, as well as biofilm formation by them. This creates the need to develop new approaches for the prevention and treatment of UTIs, among which phage therapy has a dominant potential to eliminate uropathogens within urinary tract. Due to the growing interest in such therapy in the last decade, the bacteriophages (natural, genetically modified, engineered, or combined with antibiotics or disinfectants) represent an innovative antimicrobial alternative and a strategy for managing the resistance of uropathogenic microorganisms and controlling UTIs.
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Phenolic compounds from Nerium oleander leaves: microwave assisted extraction, characterization, antiproliferative and cytotoxic activities
- Siham Ayouaz
- Sheila Cristina Oliveira-Alves
- Khalef Lefsih
- Ana Teresa Serra
- Andreia Bento da Silva
- Madani Samah
- Jakub Karczewski
- Khodir Madani
- Maria Rosário Bronze
A microwave-assisted extraction (MAE) method was used for the extraction of phenolic compounds from Nerium oleander leaves. The influence of variables such as ethanol concentration, microwave power, irradiation time and liquid/solid ratio on polyphenol extraction was modelled using a second-order regression equation based on response surface methodology (RSM). The optimal conditions for MAE were: extraction solvent 35% ethanol concentration, 500 W microwave power, 60 s irradiation time and a solvent/material ratio of 20 mL g−1. Under optimal MAE conditions, the recovery of TPC was 25.752 mg GAE per g dw. 19 compounds have been identified by HPLC-ESI-MS/MS analysis; the main compounds identified were chlorogenic acid, rutin and quinic acid esters, such as caffeoylquinic acids and dicaffeoylquinic acids. Additionally, the optimized extract demonstrated potential to inhibit HT29 colorectal cancer cell growth (EC50 = 2.432 μg mL−1) without presenting cytotoxicity in confluent Caco-2 cells, a model of human intestinal epithelium. These results supply new information about the phenolic composition of Nerium oleander leaves and their antiproliferative effect.
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Photochemical Rearrangement of a 19-Membered Azoxybenzocrown: Products and their Properties
- Ewa Wagner-Wysiecka
- Paulina Szulc
- Elżbieta Luboch
- Jarosław Chojnacki
- Katarzyna Szwarc-Karabyka
- Natalia Łukasik
- Miłosz Murawski
- Michał Kosno
The preparation and characterization of products of the chemical and photochemical rearrangements of a 19-membered o,o'-azoxybenzocrown were presented. In photochemical rearrangement, besides expected product i.e. 19-membered o-hydroxy-o,o'-azobenzocrown (19-o-OH), obtained under defined conditions with 75% yield, also other macrocyclic products were isolated and identified, namely: 19-membered p-hydroxy-o,o'-azobenzocrown (19-p-OH), 21-membered o'-hydroxy-o,p'-azobenzocrown (21-o'-OH) and 19-membered macrocycle containing 5-membered ring bearing an aldehyde group (19-al). The structures of two atypical products of the photochemical rearrangement - 21-o'-OH and 19-al - were determined in the solid state by the X-ray method and in solution using NMR spectroscopy. Tautomeric equilibrium of the formed hydroxyazobenzocrowns and its change depending on acidity/basicity of the environment and alkali and alkaline earth metal cations complexation were studied using UV-Vis spectrophotometry, spectrofluorimetry and 1H NMR spectroscopy.